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Updated: 03:39 EST, 12 December 2011
Little Mix last night made X Factor history as they became the first group ever to win the ITV talent show.
Jesy Nelson, Perrie Edwards, Leigh-Anne Pinnock and Jade Thirlwall beat fellow finalist Marcus Collins at the final hurdle to take home the crown after a series of stunning performances on the final show.
Screaming with delight as they were told they had won the show, the girls burst into tears before speaking to host Dermot O'Leary.
The treatment has less negative effects compared with typical radiotherapy. Jude Childrens Research study Health center
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